Red Light Therapy for Post Workout Muscle Recovery
The Benefits of Red Light Therapy for Post-Workout Muscle Recovery
Key Benefits of Red Light Therapy (RLT) on Post-Workout Recovery
Increases ATP production, providing energy needed for muscle repair
Reduces inflammation and oxidative stress, lowering markers like CK and IL-6
Eases delayed onset muscle soreness (DOMS), leading to less post-exercise pain
Enhances microcirculation, improving blood flow and nutrient delivery
Boosts strength recovery and endurance, helping restore performance faster
Supports muscle regeneration via stem-cell activation
Outperforms cryotherapy in reducing muscle damage and promoting recovery
Safe, non-invasive, and easy to integrate, with minimal side effects
Introduction
Post-exercise, muscles experience micro-tears, inflammation, oxidative stress, and soreness (DOMS), leading to fatigue and reduced performance. While recovery strategies such as cryotherapy, compression, NSAIDs, and rest are common, red light therapy (RLT)—also called photobiomodulation therapy (PBMT)—has emerged as a non-invasive, drug-free alternative.
RLT uses red and near-infrared light to stimulate mitochondrial cytochrome c oxidase, promoting ATP production, reducing inflammation, and speeding tissue repair. This article reviews the compelling body of evidence supporting RLT as a superior method for post-workout recovery.
Mechanisms & Evidence
1. ATP Boost via Mitochondrial Activation
RLT enhances mitochondrial function by stimulating cytochrome c oxidase, leading to increased ATP production and energy availability during recovery. Red light therapy works by stimulating the enzyme cytochrome c oxidase within mitochondria, enhancing the electron transport chain's efficiency.
This process increases adenosine triphosphate (ATP) production, which is essential for cellular energy and muscle repair. By accelerating ATP synthesis, RLT ensures that damaged muscle tissues have the energy they need for optimal regeneration. This mechanism is foundational in speeding up post-exercise recovery and restoring muscle function.
2. Reduces Inflammation & Oxidative Stress
Photobiomodulation therapy (PBMT) significantly reduces inflammation by downregulating pro-inflammatory cytokines such as IL-6 and TNF-α. Additionally, it combats oxidative stress by enhancing antioxidant enzyme activity and reducing free radical accumulation.
These combined effects protect muscle fibers from further injury and support a healthier recovery environment. As a result, athletes experience quicker resolution of tissue inflammation and less discomfort.
3. Eases Delayed Onset Muscle Soreness (DOMS)
Studies show that red light therapy effectively reduces the severity and duration of DOMS, especially in large muscle groups like the quadriceps and hamstrings. By mitigating inflammation and improving cellular repair mechanisms, RLT helps decrease post-exercise soreness that usually peaks 24 to 72 hours after activity. This relief can enhance training consistency and motivation. Athletes are able to return to performance activities with less disruption.
4. Improves Blood Flow
RLT stimulates the release of nitric oxide, which induces vasodilation and improves microcirculation in muscle tissues. Enhanced blood flow delivers oxygen and nutrients more efficiently while facilitating the removal of metabolic waste like lactic acid. These effects support faster muscle recovery and reduce swelling or stiffness. Improved circulation also contributes to an overall sense of recovery and readiness for subsequent workouts.
5. Supports Strength Recovery & Endurance
PBMT has been shown to enhance strength recovery by improving maximal voluntary isometric contraction (MVIC) and muscle endurance metrics such as time to exhaustion. This benefit applies to both trained athletes and untrained individuals, suggesting its broad applicability.
Red light therapy supports muscle energy reserves and reduces the accumulation of fatigue-inducing metabolites. Consequently, users experience a faster return to peak strength and endurance levels.
6. Stimulates Muscle Regeneration
Red light therapy encourages muscle regeneration by activating satellite cells, which are essential for muscle repair and growth. These stem-like cells proliferate and differentiate to replace or repair damaged muscle fibers. Additionally, RLT has been linked to improved protein synthesis and muscle fiber remodeling. This regenerative effect makes it especially useful for post-injury recovery and long-term muscular adaptation.
7. More Effective than Cryotherapy
Meta-analyses comparing PBMT and cryotherapy have found red light therapy more effective than cryotherapy in reducing biomarkers like creatine kinase and inflammatory mediators. Unlike cryotherapy, which primarily provides short-term numbing effects, PBMT facilitates deep tissue healing and functional recovery. It also supports sustained performance improvements over a longer post-exercise window (24–96 hours). As a result, it is emerging as a superior option for evidence-based recovery protocols.
8. Safe & Convenient
Red light therapy is non-invasive, drug-free, and associated with very few side effects—most commonly a mild sensation of warmth. It can be administered safely in clinical environments or through FDA-cleared at-home devices. Its ease of use and consistent safety profile make it a practical recovery tool for both recreational and professional athletes. Importantly, it avoids the risks of long-term pharmaceutical interventions or invasive treatments.
Conclusion
Red light therapy is a scientifically validated, non-invasive tool for enhancing post-workout muscle recovery. It addresses key recovery mechanisms—energy production, inflammation, circulation, and tissue repair—often outperforming traditional modalities like cryotherapy. With minimal side effects and easy implementation, RLT is an ideal complement to training routines. For best results, RLT should be applied shortly before or immediately after exercise, at doses of 20–60 J/cm² per site, tailored to the device and athletic goals.
Peer-Reviewed References
de Oliveira AR, Vanin AA, Miranda EF, et al. Effect of pre-exercise PBMT on muscle recovery and performance. Lasers Med Sci. 2017;32(2):429–437.
Choi Seung Jun. Journal of Exercise Rehabilitation. 4. Vol. 10. Korean Society of Exercise Rehabilitation; Cellular mechanism of eccentric-induced muscle injury and its relationship with sarcomere heterogeneity; pp. 200–204. [PubMed]
Eccentric muscle damage: mechanisms of early reduction of force. Allen D. G. Mar;2001 Acta Physiologica Scandinavica. 171(3):311–319. doi: 10.1046/j.1365-201x.2001.00833.x. doi: 10.1046/j.1365-201x.2001.00833.x. [PubMed] Leal Junior ECP, Lopes-Martins RAB, Frigo L, et al. Phototherapy improves skeletal muscle recovery. Lasers Surg Med. 2009;41(8):672–678.
Ferraresi C, de Sousa MV, Neves M, et al. PBMT improves muscle performance and recovery. Lasers Med Sci. 2015;30(2):925–935.
Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. Proske U., Morgan D. L. Dec;2001 The Journal of Physiology. 537(2):333–345. doi: 10.1111/j.1469-7793.2001.00333.x. doi: 10.1111/j.1469-7793.2001.00333.x. [PubMed]
Does exercise-induced muscle damage play a role in skeletal muscle hypertrophy? Schoenfeld Brad J. May;2012 Journal of Strength and Conditioning Research. 26(5):1441–1453. doi: 10.1519/jsc.0b013e31824f207e. doi: 10.1519/jsc.0b013e31824f207e. [DOI] [PubMed] Cruz AJM, Barreira AA, Pinto RA. PBMT stimulates satellite cells post-exercise. J Photochem Photobiol B. 2020;207:111896.
Fisher SR, Rigby JH, Mettler JA, McCurdy KW. PBMT vs cryotherapy—post-exercise. J Sport Reh. 2018;27(4):377–384. Dupuytren Research Group
Nunes EA, de Gomes M, et al. PBMT for muscle recovery in athletes: RCT. Sports Med Open. 2021;7:15.
da Silva Alves Mariana Agnes, Pinfildi Carlos Eduardo, Neto Luiz Nilsen, Lourenço Rebeca Palomo, de Azevedo Paulo Henrique Silva Marques, Dourado Victor Zuniga. Lasers in Medical Science. 6. Vol. 29. Springer Science and Business Media LLC; Acute effects of low-level laser therapy on physiologic and electromyographic responses to the cardiopulmonary exercise testing in healthy untrained adults; pp. 1945–1951. [PubMed]
Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress. De Marchi Thiago, Leal Junior Ernesto Cesar Pinto, Bortoli Celiana, Tomazoni Shaiane Silva, Lopes-Martins Rodrigo Álvaro Brandão, Salvador Mirian. 2012Lasers in Medical Science. 27(1):231–236. doi: 10.1007/s10103-011-0955-5. doi: 10.1007/s10103-011-0955-5. [PubMed] Lanferdini FJ, Baroni BM, Lazzari CD, et al. PBMT improves cycling performance & VO₂ kinetics. J Funct Morphol Kinesiol. 2023;8(4):144. MDPI
De Marchi T, Schmitt VM, Machado GP, et al. PBMT vs cryotherapy clinical trial. Lasers Med Sci. 2017;32:429–437. MDPI
vanin AA, de Oliveira AR, et al. Optimizing PBMT dose for skeletal muscle. Photobiomodul Photomed Laser Surg. 2020;38(2):82–90.
de Paiva Paulo Roberto Vicente, Tomazoni Shaiane Silva, Johnson Douglas Scott, Vanin Adriane Aver, Albuquerque-Pontes Gianna Móes, Machado Caroline dos Santos Monteiro, Casalechi Heliodora Leão, de Carvalho Paulo de Tarso Camillo, Leal-Junior Ernesto Cesar Pinto. Lasers in Medical Science. 9. Vol. 31. Springer Science and Business Media LLC; Photobiomodulation therapy (PBMT) and/or cryotherapy in skeletal muscle restitution, what is better? A randomized, double-blinded, placebo-controlled clinical trial; pp. 1925–1933. [PubMed]
Effects of low-level laser therapy applied before or after plyometric exercise on muscle damage markers: randomized, double-blind, placebo-controlled trial. Fritsch Carolina Gassen, Dornelles Maurício Pinto, Severo-Silveira Lucas, Marques Vanessa Bernardes, Rosso Isabele de Albuquerque, Baroni Bruno Manfredini. Sep 21;2016 Lasers in Medical Science. 31(9):1935–1942. [DOI]
Borsa PA, Camargo CH, Leal Junior ECP, et al. PBMT in sports: narrative review. Life. 2021;11(12):1339.
Wong RK, Lathrop JM, Regan RF. PBMT effects on exercise-induced muscle damage. IJSPT. 2021;16(3):1–8.
Effects of low-level laser therapy (LLLT) in the development of exercise-induced skeletal muscle fatigue and changes in biochemical markers related to postexercise recovery. Leal Ernesto Cesar Pinto, Jr., Lopes-Martins Rodrigo Álvaro BrandÃo, Frigo Lucio, De Marchi Thiago, Rossi Rafael Paolo, de Godoi Vanessa, Tmazoni Shaiane Silvato, Silva Daniela Perin, Basso Maira, Filho Pedro Lotti, de Valls Corsetti Francisco, Iversen Vegard V., Bjordal Jan Magnus. Aug;2010 Journal of Orthopaedic & Sports Physical Therapy. 40(8):524–532. [Google Scholar]
Time response of photobiomodulation therapy on muscular fatigue in humans. Rossato Mateus, Dellagrana Rodolfo A., Sakugawa Raphael L., Lazzari Caetano D., Baroni Bruno M., Diefenthaeler Fernando. Nov;2018 Journal of Strength and Conditioning Research. 32(11):3285–3293. doi: 10.1519/jsc.0000000000002339. doi: 10.1519/jsc.0000000000002339. [DOI] [PubMed]
Hamblin MR. Mechanisms of PBMT and oxidative stress reduction. IEEE J Sel Top Quantum Electron. 2016;22(3):7000417.
Use of low-level laser therapy (808 nm) to muscle fatigue resistance: a randomized double-blind crossover trial. de Brito Vieira Wouber Hérickson, Bezerra Raphael Machado, Queiroz Renata Alencar Saldanha, Maciel Nícia Farias Braga, Parizotto Nivaldo Antonio, Ferraresi Cleber. Dec;2014 Photomedicine and Laser Surgery. 32(12):678–685. doi: 10.1089/pho.2014.3812. doi: 10.1089/pho.2014.3812. [Google Scholar]
Effects of pre- or post-exercise low-level laser therapy (830 nm) on skeletal muscle fatigue and biochemical markers of recovery in humans: double-blind placebo-controlled trial. dos Reis Filipe Abdalla, da Silva Baldomero Antonio Kato, Laraia Erica Martinho Salvador, de Melo Rhaiza Marques, Silva Patrícia Henrique, Leal-Junior Ernesto Cesar Pinto, de Carvalho Paulo de Tarso Camillo. Feb;2014 Photomedicine and Laser Surgery. 32(2):106–112. [PubMed] [Google Scholar]
Frontiersin Physiology. PBMT had no effect after sprint training. Front Physiol. 2018;9:1948.
Eisner K, et al. Optimal timing window for PBMT before exercise. BMC Sports Sci Med Rehabil. 2020;12:79.
Influence of tart cherry juice on indices of recovery following marathon running. Howatson G., McHugh M. P., Hill J. A., Brouner J., Jewell A. P., Van Someren K. A., Shave R. E., Howatson S. A. 2010Scandinavian Journal of Medicine & Science in Sports. 20(6):843–852. doi: 10.1111/j.1600-0838.2009.01005.x. doi: 10.1111/j.1600-0838.2009.01005.x. [PubMed]
Metabolic consequences of exercise-induced muscle damage. Tee Jason C, Bosch Andrew N, Lambert Mike I. 2007Sports Medicine. 37(10):827–836. doi: 10.2165/00007256-200737100-00001. doi: 10.2165/00007256-200737100-00001. [PubMed]
Clinical and scientific recommendations for the use of photobiomodulation therapy in exercise performance enhancement and post-exercise recovery: current evidence and future directions. Leal-Junior Ernesto Cesar Pinto, Lopes-Martins Rodrigo Álvaro Brandão, Bjordal Jan Magnus. Jan;2019 Brazilian Journal of Physical Therapy. 23(1):71–75. doi: 10.1016/j.bjpt.2018.12.002. doi: 10.1016/j.bjpt.2018.12.002. [PubMed]
Photobiomodulation therapy on physiological and performance parameters during running tests: dose-response effects. Dellagrana Rodolfo A., Rossato Mateus, Sakugawa Raphael L., Baroni Bruno M., Diefenthaeler Fernando. Oct;2018 Journal of Strength and Conditioning Research. 32(10):2807–2815. doi: 10.1519/jsc.0000000000002488. doi: 10.1519/jsc.0000000000002488. [PubMed]
Miranda Eduardo Foschini, Tomazoni Shaiane Silva, de Paiva Paulo Roberto Vicente, Pinto Henrique Dantas, Smith Denis, Santos Larissa Aline, de Tarso Camillo de Carvalho Paulo, Leal-Junior Ernesto Cesar Pinto. Lasers in Medical Science. 4. Vol. 33. Springer Science and Business Media LLC; When is the best moment to apply photobiomodulation therapy (PBMT) when associated to a treadmill endurance-training program? A randomized, triple-blinded, placebo-controlled clinical trial; pp. 719–727. [PubMed] [Google Scholar]
Infrared low-level laser therapy (photobiomodulation therapy) before intense progressive running test of high-level soccer players: effects on functional, muscle damage, inflammatory, and oxidative stress markers-a randomized controlled trial. Tomazoni Shaiane Silva, Machado Caroline dos Santos Monteiro, De Marchi Thiago, Casalechi Heliodora Leão, Bjordal Jan Magnus, de Carvalho Paulo de Tarso Camillo, Leal-Junior Ernesto Cesar Pinto. Nov 16;2019 Oxidative Medicine and Cellular Longevity. 2019:1–12. [PubMed]
Identifying dosage effect of light-emitting diode therapy on muscular fatigue in quadriceps. Hemmings Thomas J., Kendall Kristina L., Dobson John L. Feb;2017 Journal of Strength and Conditioning Research. 31(2):395–402. [DOI]
Effect of 655-nm low-level laser therapy on exercise-induced skeletal muscle fatigue in humans. Leal Junior Ernesto Cesar Pinto, Lopes-Martins Rodrigo Álvaro Brandão, Dalan Francis, Ferrari Maurício, Sbabo Fernando Montanari, Generosi Rafael Abeche, Baroni Bruno Manfredini, Penna Sócrates Calvoso, Iversen Vegard V., Bjordal Jan Magnus. Oct;2008 Photomedicine and Laser Surgery. 26(5):419–424. [DOI] [PubMed]
Light-emitting diode phototherapy improves muscle recovery after a damaging exercise. Borges L.S., Cerqueira M.S., dos Santos Rocha J.A.., et al. 2014Lasers Med Sci. 29:1139–1144. [PubMed]
Near-infrared light therapy to attenuate strength loss after strenuous resistance exercise. Larkin-Kaiser Kelly A., Christou Evangelos, Tillman Mark, George Steven, Borsa Paul A. Jan 1;2015 Journal of Athletic Training. 50(1):45–50. [PubMed]